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Playdoh is Mozilla's starter kit for new Django projects. It aims to be secure-by-default and set up all the same goodies we use to scale for high traffic, perform background tasks, localize our sites in many languages, and other cool things.
It's a great new open source tool that helps you support all versions of python with your existing automated tests. It's not a test runner, it's a super test runner runner! Or something. There is no easy way to describe it which is why the front page of the website is sort of confusing, IMO. We use tox on the Nose project to make sure each code change doesn't break the tests in Python 2.4, 2.5, 2.6, 2.7, 3.0 or Jython. Not everybody targets so many environments but if you want to maintain a widely used module then you probably will want to use tox someday.