GRR Rapid Response (https://github.com/google/grr) is an incident response framework focused on remote live forensics.
It consists of a Python client (agent) that is installed on target systems, and Python server infrastructure that can manage and talk to clients. The goal of GRR is to support forensics and investigations in a fast, scalable manner to allow analysts to quickly triage attacks and perform analysis remotely.
GRR was started at Google in 2009 as a simple Python helper script used by Incident Response engineers. Eventually a little Python script got a little server component, was adapted to run on multiple systems (Mac, Linux, Windows), then a little UI was added and a few nice features were introduced (large-scale hunts, collection of predefined artifacts, memory analysis). A helper script has eventually evolved into a sophisticated framework with 180,000 lines of Python code.